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It is not found in nature in its isolated form but is derived from a larger protective protein present in gastric secretions

Furthermore, the development of sustained-release nanoformulations (such as the Tf-LP-ERN system) is key for maintaining therapeutic plasma concentrations and avoiding high fluctuations that may exacerbate toxicity (136)

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[ 6 ] Additionally, throughout the 1980s, DSIP was also researched for its potential influence on endocrine function, stress response, pain perception, and the effects of drugs such as morphine and amphetamines