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Biosci Rep 17:293302, PMID: 9337484 Sato T, Machida T, Takahashi S, Iyama S, Sato Y, Kuribayashi K, Takada K, Oku T, Kawano Y, Okamoto T, Takimoto R, Matsunaga T, Takayama T, Takahashi M, Kato J, Niitsu Y (2004) Fas-mediated apoptosome formation is dependent on reactive oxygen species derived from mitochondrial permeability transition in Jurkat cells

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Clinical practice suggests that antithyroid drugs combined with -adrenergic receptor antagonists can be used as effective drugs for the treatment of mental disorders and psychiatric symptoms caused by hyperthyroidism, as the excessive activation of the adrenal system induced by hyperthyroidism can lead to somatic symptoms (14)

It is present in the cytoplasm and organelles

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