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group, the oral bioavailability was determined to be extremely low (0.025%) in rats, based on the assumption of linear pharmacokinetics

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These molecular signals trigger cascading cellular responses that continue independently after the peptide itself has been metabolized

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Common variants include: GSTM1 null : 40-50% of population-reduced capacity to neutralize environmental toxins GSTP1 variants : Impaired detoxification of carcinogens 6

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