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doi: 10.1186/s43556-025-00264-9, 3

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6 Discussion Recent evidence firmly establishes taste perception as a critical link between sensory biology and metabolic regulation, mediated by a complex neuroendocrine crosstalk within the gut-brain-taste axis

Thyroid hormones profoundly influence basal metabolic rate, thermogenesis, and energy expenditure, making thyroid status a critical factor when evaluating any weight management intervention