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Additionally, a recent open-label randomized trial showed that semaglutide significantly reduced serum IL-6 and CRP levels in PsO T2DM patients, compared to controls not on semaglutide therapy, reinforcing the anti-inflammatory effects of GLP-1RAs (45)

For context, Hims has continued offering compounded semaglutide after the FDA declared there was no longer a shortage of the brand-name version (meaning: this regulatory exemption no longer applies)

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Theres a key similarity across both nations: its the more affluent demographic that is using GLP-1s the most

The IC50 and Ki of saxagliptin indicate that saxagliptin is an effective competitive inhibitor of DPP-4