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In addition to their insulinotropic effects, GIP and GLP-1 play critical roles in various biological processes in different tissues and organs that express GIPR and GLP-1R, including the pancreas, fat, bone and the brain
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Read the full review To view or add a comment, sign in Excited to share our latest publication in Molecular Pharmacology: Identification and Characterization of Selective Inhibitors of Nav1.9 VoltageDependent Sodium Channels. In this study, we present what we believe to be the first detailed pharmacological characterization of this therapeutically important sodium channel, along with the discovery and initial profiling of a potent, subtypeselective class of Nav1.9 inhibitors
The answer isnt clear
doi: 10.1056/NEJMoa2030183 67 McGuireDKShihWJCosentinoFCharbonnelBCherneyDZIDagogo-JackSet al
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