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The study also confirmed previous findings that GLP-1 receptor agonists protect cardiovascular health, with a 14% reduction in the risk of cardiovascular death, non-fatal heart attack, and non-fatal stroke, compared to placebo
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Possible long-term effects are unclear
When calories are restricted or food intake changes rapidly, hormonal systems respond by increasing hunger signals and reducing metabolic efficiency
thus, these lab-engineered hormones work by stimulating insulin production and delaying gastric emptying, alongside signaling fullness to the brain
Effect of Subcutaneous Tirzepatide vs Placebo added to titrated insulin glargine on Glycemic Control in patients with type 2 diabetes: the SURPASS-5 Randomized Clinical Trial
