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GLP-1 medications create a series of events: Your pancreas releases more insulin Glucagon (what triggers blood sugar release) is blocked Gastric emptying slows down (so you feel full longer) When you feel satisfied, youre less likely to overeat, and you may find it easier to stick with your daily calorie budget
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Additionally, passive permeability through the intestinal epithelium is limited, and P-glycoprotein (MDR1) actively effluxes ESC back into the intestinal lumen, further decreasing absorption (Zhang et al
Your GP will take a thorough history, including details about your menstrual cycle, contraception, medications (including Ozempic), and any associated symptoms