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These categories differ in the magnitude and direction of receptor activation, enabling tailored therapeutic applications depending on disease mechanisms and required biological responses

In one clinical trial, 5 mg per week tirzepatide was slightly more effective than 1 mg per week semaglutide in reducing body weight and glycated hemoglobin (HbA1c)

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Ongoing research suggests these drugs may have even broader benefits, so staying informed about regulatory updates is more important than ever

First, there was clinical heterogeneity due to the different characteristics of the populations and the different follow-up times

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