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Killion EA et al (2020) Glucose-Dependent Insulinotropic Polypeptide Receptor Therapies for the Treatment of Obesity, Do Agonists = Antagonists

The interaction of sodium and zinc in the priming of T cell subpopulations regarding Th17 and treg cells

But its firmly on the map

The FDAs Cardiovascular and Renal Drugs Advisory Committee voted 9-3 that patisirans benefits outweigh its risks in this indication, despite concerns expressed in FDA briefing documents prior to the adcomm meeting

The drugs are contraindicated in pregnant women due to risk of developmental abnormalities in the foetus

10.1016/0014-5793(89)81332-8 FEBS Lett