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Case methodology disclosed Health Canada reviewed 15 cases of suicide, self-harm and suicidal/self-harm ideation in patients using GLP-1 RAs, including 3 Canadian and 12 international reports, with 2 drawn from published literature

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Additionally, we analyze its potential as multidisease biomarker, crosstalk mediator, and therapeutic target, providing new strategies and perspectives for drug research and the prevention and treatment of various diseases