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It affects the GLP one receptor but also the GIP receptor, which are both involved in hunger and satiety and motility. Dan Azagury, MD, FACS, the chief bariatric surgeon and medical director of Stanford University School of Medicines Lifestyle and Weight Management Clinic in California, who also was not involved in the Eli Lilly study, told Healthline that he was not surprised at the studys results

Moreover, a recent SURPASS-3 MRI substudy has shown that tirzepatide may be more effective in reducing liver fat than insulin degludec [93]

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Journals.physiology.org, 2011, www.journals.physiology.org/doi/full/10.1152/japplphysiol.00945.2010

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