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For severe obesity specifically, these are not comparable outcomes

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doi: 10.1089/thy.2014.0525 101 MandelSJMandelL

You typically start at a low dose of 0.8 mg and gradually increase your dosage over a period of 3090 days

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Typically occurring between ages 45 and 55, perimenopause transition is characterized by fluctuating estrogen levels and declining ovarian function that initiate a cascade of physiological and psychological changes that extend far beyond reproductive health