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Abbreviations ACC: American College of Cardiology ADA: American Diabetes Association ASCVD: Atherosclerotic cardiovascular disease BMI: Body mass index CI: Confidence interval CV: Cardiovascular CVD: Cardiovascular disease CVOT: Cardiovascular outcomes trial DPP-4: Dipeptidyl peptidase-4 EASD: European Association for the Study of Diabetes EDTA: European Dialysis and Transplant Association eGFR: Estimated glomerular filtration rate ERA: European Renal Association ESC: Europe Society of Cardiology ESRD: End-stage renal disease EURECA-m: European Renal and Cardiovascular Medicine FDA: U.S

H., Brown-Frandsen, K., et al

Product Specifications CAS Number: 910463-68-2 Synonym: NN9535 Peptide Sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc--Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-OH Molecular Formula: CHNO Molecular Weight: 4113.6 g/mol Purity: 95% (verified by HPLC and mass spectrometry) Packaging Format: 2 mg lyophilized powder in sealed research-grade vial Storage Conditions: Store 28 C (20 C long term)

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