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Non-pharmacological approaches should not be overlooked and often form the foundation of chronic pain management: Physical therapies physiotherapy, exercise programmes, and stretching can address musculoskeletal pain Heat and cold therapy simple but effective for many pain types Weight management particularly relevant for fatty liver patients, as weight loss can improve both liver health and reduce pain from weight-bearing joints Psychological approaches cognitive behavioural therapy (CBT) and mindfulness-based stress reduction for chronic pain For severe or chronic pain unresponsive to simple measures, referral to a pain management specialist may be appropriate
People with kidney disease, hypothyroidism, seizure disorders, or those taking warfarin should seek medical advice before using L-carnitine supplements
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It is still too early to draw definitive conclusions, but the numerous ongoing clinical trials, including the cardiovascular safety trial versus an active comparator (dulaglutide), the first of its kind, will provide us shortly with important confirmations
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