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Heteroatom Chemistry

During reperfusion, a large influx of oxygen molecules into the damaged tissue triggers a burst of ROS, activating inflammatory signaling pathways such as NF-B, promoting neutrophil infiltration and the release of inflammatory factors, thereby forming an oxidative stress-inflammatory response feedback loop

5C), indicating sustained local presence and mucosal coverage of the formulation

The study was approved by the Regional Ethics Committee in Stockholm, Sweden

PloS One (2017) 12:e0179889