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MemAID: memory advancement with intranasal insulinvs
Nature 521 , 180185 (2015)
The accelerated approval was granted based on initial overall response rate (ORR) of 57% in 164 treatment-nave patients and duration of response (DOR)40% of responders had a duration of response greater than 12 months, according to the FDAs full approval announcement
These medications slow gastric emptying, reduce appetite, and improve insulin sensitivity
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