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doi: 10.1038/s41598-020-74022-y

Similarly, in the A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes (SOUL) study, which randomized patients with type 2 diabetes and atherosclerotic cardiovascular disease, chronic kidney disease, or both to oral semaglutide versus placebo, the primary outcome of major adverse cardiovascular event occurred in 12.0% of the patients receiving semaglutide and 13.8% of the patients receiving placebo (hazard ratio, 0.86

Other problems included iron deficiency (3.2%) and B vitamin deficiency (2.6%)