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J Clin Pharmacol 36:13-24 1996
Potential benefit - A patient whose biomarkers suggest rapid metabolism of GLP-1 drugs might be offered a longer-acting formulation, while someone with strong GIP responsiveness could start on a dual-agonist right away, avoiding months of trial-and-error
Similarly, preclinical research involving animals must comply with Institutional Animal Care and Use Committee (IACUC) directives and adhere to Animal Welfare Act (AWA) standards
Because compounded medications are not FDA-regulated, going this route does have some inherent risks
Drug Metab Pharmacokinet
The gene expression changes the peptide triggers may be more important than continuous peptide presence
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