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Long-term antibiotics may reduce biotin-producing gut bacteria
In addition to its metabolic functions, biotin may also influence gene regulation: it can attach to specific lysine residues on histone proteins (a process known as histone biotinylation), thereby potentially affecting chromatin structure and gene expression
Both of which regulate mitochondrial biogenesis and shift substrate utilization from glucose toward fatty acid oxidation
As you are technically absorbing lower amounts of B12 over time, you may have to wait for your symptoms to reduce
Vitamin B12, Nerves and Myelin Vitamin B12 is a central nutrient in the creation and maintenance of the myelin sheaths, lipid-rich protective layers which cover the nerves
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