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[Crossref] [PubMed] Tal R, Heck M, Teloken P, et al

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Retatrutide: The Triple Agonist That Could Redefine Metabolic Medicine

Patients who had used a semaglutide were categorized into cohorts based on when they discontinued the semaglutide before surgery: 30 days prior to surgery , n=482 patients 14 days prior to surgery, n=591 patients 7 days prior to surgery, n=680 patients 5 days prior to surgery, n=758 patients 3 days prior to surgery, n=777 patients 1 day prior to surgery, n=706 patients Did not stop a semaglutide prior to surgery, n=170 patients These patients were compared to a control group of 206,005 patients with no history of semaglutide use

oral semaglutide up to 40 mg was safe and tolerable with the overall safety profile consistent with that of the GLP-1RA class [65]