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Luger, Are melanocortin peptides future therapeutics for cutaneous wound healing?, Wiley, Feb

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The spot might feel a little tender for a short while afterwards, but it fades fast

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Semaglutide and tirzepatide are "upstream" they act on incretin receptors to influence appetite regulation, gastric emptying, and glucose-dependent insulin secretion

Again, the evidence for this is preliminary, and the research has primarily involved animal or lab studies, not human