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The implications of human metabolic network topology for disease comorbidity

A randomized placebo-controlled trial in 1,228 CKD patients receiving maintenance hemodialysis found that 4 grams of fish oil (providing 1.6 grams of EPA and 0.8 grams of DHA) daily for 3.5 years reduced the rate of serious cardiovascular events by 43%

doi: 10.1016/j.celrep.2018.03.070 280 ChuAYWorkalemahuTPaynterNPRoseLMGiulianiniFTanakaTet al

doi: 10.1016/j.phrs.2020.105131 109 GonzalezGAOsujiEUFiurNCClarkMGMaSLukovLLet al

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