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Vitamin C Pros: Glutathione Regeneration: Converts oxidised glutathione back into its active form

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Studies in cultures of mixed intestinal epithelial cells and in model enteroendocrine cells (e.g., STC-1 and GLUTag) have demonstrated the expression of the bile acid G protein-coupled receptor, TGR5, and the ability of bile acids to activate TGR5 and stimulate GLP-1 secretion (Kidd et al., H 2 S, produced as a byproduct by luminal sulfate-reducing commensal bacteria in the colon or as an endogenous signaling molecule synthesized from L-cysteine mainly via cystathionine--lyase (CSE) and cystathionine--synthase (CBS), and to lesser extent by 3-mercaptopyruvate sulfurtransferase (3-MST), regulate various physiological functions such as secretion, motility and visceral nociception (Robert et al., 2010

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These drugs work on multiple fronts: Blood Sugar Control: They stimulate insulin release and inhibit glucagon a hormone that raises blood sugar