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What they found (summary): MC1R: melanogenesis, pigmentation, anti-inflammation MC2R: ACTH receptor in the adrenals (Melanotan II does not act) MC3R: energy, cardiovascular function, anti-inflammation MC4R: appetite (central control), sexual function, autonomic regulation MC5R: exocrine glands (sebaceous, lacrimal, salivary) Mutations in MC4R are the most common monogenic cause of obesity in humans Why it matters: Cones review article is the reference article for all of melanocortin pharmacology
Do not use while trying to conceive, pregnant, or breastfeeding without medical guidance
Hong B, Kim H, Lee D, Kim K
Atwood, J
Potent prearranged positive allosteric modulators of the glucagon-like peptide-1 receptor
Boiga eggs are very thick so I have made it a practice to wait for one baby to pip first and then I will manually pip all of the eggs at that point
