These studies highlighted several anti-cancer effects exerted by metformin on TC cells including: i) induction of cell death, ii) reduction of cell growth, iii) inhibition of the metastatic potential iv) modulation of chemokines in the tumor microenvironment, v) de-differentiating effects (increase in iodine up-take) (Klubo-Gwiezdzinska et al., 2013
Monitor weight, waist circumference, get labs every 46 weeks (fasting glucose or A1c if relevant), track your digestive symptoms, and mood (given emerging evidence of small antidepressant effects)
doi: 10.1097/FTD.0000000000000739 [PubMed] Torbey, M
Telehealth options allow you to complete visits from home, reducing the need for travel or time off work
Most people report feeling essentially normal, with minimal noticeable changes
Side effect management becomes important with exogenous Testosterone