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With a half-life of only 13 hours, liraglutide creates a much more pronounced peak-and-trough pattern within each 24-hour period

This is the physical destruction of the otolithic bed

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GLP analogs (other than lixisenatide) are contraindicated in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) or a family history of medullary thyroid carcinoma