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Scalp inflammation is increasingly recognised as a factor in androgenetic alopecia progression

4.11 SURMOUNT-CN: tirzepatide for weight loss in Chinese obese and overweight adults The SURMOUNT-CN trial recruited 210 obese or overweight adult patients in China, who received weekly doses of tirzepatide (10 mg, 15 mg) or placebo for 52 weeks

Methotrexate reduces inflammatory cell numbers, expression of monokines and of adhesion molecules in synovial tissue of patients with rheumatoid arthritis

The clinical pipeline represents diverse approaches to differentiation, including alternative receptor combinations, novel delivery mechanisms, and improved tolerability profiles

Both of these effects were canceled in the presence of an antagonist of melanocortin receptors 3 and 4, confirming receptor-mediated mechanisms

Available from: Accessed 28 June 2025 Medicines and Healthcare products Regulatory Agency