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Among participants randomized to the treatment group, women had a stronger association between decreases in body weight and improvements in KCCQ-CSS when compared to men (interaction p=0.0058)

In conclusion, the study robustly demonstrated that FOXO4-DRI selectively eliminates senescent Leydig cells, reduces detrimental SASP factor secretion, improves the testicular microenvironment, and ultimately enhances sperm quality and spermatogenesis in aged mice, positioning it as a promising therapeutic candidate for age-related male infertility [2]

Is Tirzepatide a GLP-1

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