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In the systematic review by Lauti et al

16 Additionally, glutathione increased susceptibility to tetracycline but decreased susceptibility to ciprofloxacin and kanamycin, without a significant difference in susceptibility to ampicillin and chloramphenicol, in P

Since glutathione is a key player in the liver's ability to process these toxins, a high "toxic load" can lead to lower systemic levels

However it is important to keep in mind that using products that help with pigmentation will not help prevent unwanted pigment problems that occur from Melanotan use.