is there a maintenance dose for tirzepatide What the of Tirzepatide? Maintenance therapy on semaglutide or

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J Clin Invest 124 : 24562463

Since GLP-1 medications can lead to a significant reduction in food intake, its often recommended to eat enough protein to prevent muscle loss while dropping weight

For instance, the rectal administration of taurocholic acid increased GLP-1 secretion in both healthy subjects [177] and obese type 2 diabetic volunteers [178]

Among the 14 trials included, four excluded patients with heart failure, while the remaining nine articles excluded patients with heart failure, cardiac events (e.g., myocardial infarction, unstable angina, revascularization procedure, stroke) or cardiovascular diseases ( Supplementary Table 4 )

Caution is also advised in people with severe gastrointestinal motility disorders or a history of pancreatitis