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Lancet 372:293299 Apostolova N, Gomez-Sucerquia LJ, Gortat A, Blas-Garcia A, Esplugues JV (2011) Compromising mitochondrial function with the antiretroviral drug efavirenz induces cell survival-promoting autophagy

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Estrogen decline is consolidated, the growth hormone axis has dropped further, and sarcopenia plus bone density loss become primary risks rather than emerging ones

When GH binds to its receptors, it triggers the release of IGF-1, also known as somatomedin C

doi: 10.1016/j.ejphar.2022.174941 126 Rauert-WunderlichHSiegmundDMaierEGinerTBargouRCWajantHet al