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Symptoms of deficiency, including fatigue, numbness, cognitive fog, and mood changes, may return over weeks to months
A multicenter phase II study of darinaparsin in relapsed or refractory Hodgkins and non-Hodgkins lymphoma
Treatment typically involves vitamin B12 supplementation, either through oral supplements or injections, depending on the severity of the deficiency and underlying causes.
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The induction of neuroprotective genes, such as Bcl-2 and Bcl-xl, also contributes to HGF inhibition of apoptosis (Tsuzuki et al., 2000, 2001
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