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Neuroinflammation induced by TNF- can affect the signaling of neurotrophins such as NGF and BDNF, which are essential for neuronal survival, growth, and plasticity (Saghazadeh and Rezaei 2017)
This bolstered chemoresistance in cancer cells is partially supported by glutathione synthesis via glutaminolysis 86
In addition to their traditional roles in bioenergy and biosynthesis, recent studies have also uncovered some new pathways of influence, among which PTMs of proteins in tumor cells are a particularly crucial one
These symptoms are usually mild and self-resolving
P., Fiorile, M
R.GoldringS
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