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The drug's safety profile included significant rates of nausea, vomiting, and hematologic toxicities like neutropenia and thrombocytopenia
Tretinoin (prescription retinoid): 4 of 10 (40%)
In melanoma, a novel circular RNA circPIAS1 encodes a unique 108-amino-acid peptide that significantly impedes immunogenic ferroptosis triggered by immune checkpoint blockade (ICB) therapy by regulating the balance between STAT1 SUMOylation and phosphorylation, revealing a new mechanism of immune evasion in melanoma[102]
Metabolomics in understanding the drug action mechanism of hepatitis C and related diseases At present, antiviral therapy is the main treatment for hepatitis C
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