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1999 Feb;13(2):411-8
The in vivo effects of AT-7687 were evaluated in obese cynomolgus monkeys, and when combined with the GLP-1 analogue liraglutide, AT-7687 enhances weight reduction induced by liraglutide and improves glycemic control and lipid metabolism (51)
Studies have yet to validate these benefits
Heart failure medications such as digoxin
C., Esteban-Zubero, E., Zhou, Z
Cardiovascular outcome studies Although multiple clinical trials evaluating cardiovascular events associated with GLP-1 RA use as the primary outcome are currently ongoing (Table 1), abundant non-primary outcome data are available from many clinical trials on the efficacy of GLP-1 RAs marketed earlier, such as exenatide (DURATION studies) and liraglutide (LEAD studies)
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