10.1038/ismej.2015.151 203
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Monitors for side effects like nausea (35%), diarrhea (21%), and constipation (20%)
Early-phase clinical trial data, including results from a Phase 2 randomised controlled trial published in The New England Journal of Medicine in 2023 (Jastreboff et al., NEJM 2023), demonstrated significant weight reduction in adults with obesity (without type 2 diabetes), with participants receiving the highest dose losing a mean of approximately 24% of their body weight over 48 weeks
doi: 10.1001/archpsyc.60.4.392
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