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Various topical, oral, and injection-based cosmetic skin-lightening agents with different mechanisms of action are used widely across Asia, including hydroquinone, azelaic acid, kojic acid, mulberry, alpha-arbutin, beta-arbutin, glutathione, licorice root, papaya, vitamin A (e.g., retinol), vitamin B (i.e., niacinamide), and vitamin C

References: Glutathione: Overview, uses, side effects, precautions, interactions, dosing and reviews

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Additionally, Epithalon plays a critical role in regulating the circadian rhythm by stimulating melatonin production

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