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For example, the probiotic strain Limosilactobacillus reuteri D8 activated the Wnt/-catenin signaling pathway, increasing the number of Lgr5 + and lysozyme + cells in the crypts, and stimulating epithelial proliferation both in the murine intestine and in organoid cultures (Wu et al., 2020)
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The brainstem nuclei, followed by preganglionic neurons in the IML, transmit postganglionic signals to the intestine
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Over-the-counter analgesics such as acetaminophen (Tylenol) or nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen can be used to manage acute headache episodes
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