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According to a 2012 study on a serum containing barley bioengineered epidermal growth factor, "clinical evaluations showed statistically significant improvement in the appearance of fine lines and rhytids, skin texture, pore size , and various dyschromatic conditions apparent within the first month of use, and continuing improvement trends for the duration of the study" (which was 3 months)

A useful Klow COA should match the batch number and verify every listed active in the blend

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Horst A, Kolberg C, Moraes MS, Riffel APK, Finamor IA, Bell-Klein A et al