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Science 385 , eadj1182 (2024)
How Melanotan Works & Dosing Tips Reconstitution : 10 mg vial + 5 mL bacteriostatic water = 2000 mcg/mL concentration Administration : Subcutaneous injection (typically belly fat area) Start : 10 units (200 mcg) daily for 12 weeks Maintenance : 5 units (100 mcg) 23x/week Store in refrigeration after mixing Important Notes: Results vary individually Adjust maintenance dosing for desired tan level Always wear SPF and limit sun exposure despite tanning benefits Benefits Beyond Tanning Shared by Both Melanotan I & II: Enhanced melanin production Photoprotection (UV defense) Immune system support Potential benefits for autoimmune conditions Specific to Melanotan II: Appetite suppression (supports weight management) Lipolysis (fat burning) Improved glucose and cholesterol metabolism Libido enhancement (dose-dependent) Melanotan II is sometimes used off-label as a libido booster or fat-loss peptide due to these effects
It has been studied extensively in colitis models, where it reduces intestinal inflammation through the same NF-kB suppression mechanism that benefits skin inflammation
This listing includes format, strength, CAS reference, and documentation status for procurement records
Lee 2015)
Once weekly, by subcutaneous injection
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