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doi: 10.1002/med.10001 140 TedderTF

Chem., Int

The acidic pH these products require may destabilize the copper-peptide bond, and the exfoliating action may remove copper peptides from the skin before they can be absorbed

This reinforces the need for carefully titrated regimens, especially in clinical settings where circadian timing (chronopharmacology) may dictate efficacy

To improve its inhibitory effect, the researchers optimized its structure

Gene expression modulation: Influences cellular signaling and repair pathways