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It binds to drug metabolites, alcohol byproducts (acetaldehyde), heavy metals, environmental pollutants, and other toxins through a process called glutathione conjugation
NAC is necessary to maintain healthy glutathione levels, so oral supplementation makes sense
This means AOD 9604 can be used for extended periods without diminishing returns from antibody-mediated inactivation
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In human studies, Nrf2 suppression has been linked to cataract formation in lenses collected from diabetic and older patients, with the upregulation of Keap1 (an Nrf2 suppressor) found in these individuals
is still pending, Epitalon has shown a high safety profile in studies spanning over two decades
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