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For example, 2 drugs based on the molecule tirzepatide, Mounjaro for diabetes and Zepbound for obesity, work by targeting both GLP-1 receptors and another incretin hormone known as gastric inhibitory polypeptide or GIP
The most significant clinical data on retatrutide to date come from Phase 2 trials published in 2023, including a dose-ranging study published in The New England Journal of Medicine (Jastreboff et al., NEJM 2023)
NYSE: LLY produced Mounjaro are being swept up for off-label use
Since early 2024, when the FDA cleared the first device that didnt need a prescription, the market for CGMs has exploded
Rosenstock J, Perkovic V, Johansen OE, Cooper ME, Kahn SE, Marx N, et al
Because "GLP-1" is associated with prescription drug mechanisms, companies in this category often need to be especially careful about how they describe their products to avoid implying drug-like effects
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