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It uses a methyl group donated by S-adenosylmethionine (SAM) to methylate nicotinamide a vitamin B3 form that would otherwise be recycled back into NAD+
The plasma half-life of the intact peptide is approximately 30 minutes, significantly longer than unmodified tuftsin (2-3 minutes), confirming the stabilizing effect of the Pro-Gly-Pro extension
However, as with any supplement or medication, proper dosage and medical guidance are recommended
Possible side effects may include: Patients may be advised to monitor mineral levels during therapy
Options for vitamin D supplements include: Pure Encapsulations Vitamin D 5000 IU (without Vitamin K) you can also purchase this through Fullscript
Oral dosing in anecdotal human reports ranges from 250 mcg to 500 mcg per day, with cycles lasting 4 to 12 weeks depending on the severity of the injury
