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In the absence of MPC activity, import of pyruvate into the mitochondria is greatly diminished, meaning that less acetyl-CoA can be produced by pyruvate dehydrogenase and therefore that TCA cycle flux is diminished (Gray et al., 2015

H., Wichman, J

Contribution of reduced and oxidized glutathione to signals detected by magnetic resonance spectroscopy as indicators of local brain redox state

Scientists found that there was this remarkable molecule in 1906, which now serves as an essential redox carrier

Use with caution

More comprehensive lipidomic analyses of the blood and liver from WT and KO mice are currently underway