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The SURMOUNT trials demonstrated that blood pressure effects occur in this population, with magnitude often correlating to degree of weight loss
They also interact with appetite hormones, making you less hungry but potentially more prone to nausea if you eat too quickly, too much, or the wrong foods
The best choice depends on target market, cost, stability, dosage form, and label positioning
Retatrutide slows gastric emptying significantly
Li L, Wu C-Y
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