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Tirzepatide: a Novel, once-weekly dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes

The article ties cost and coverage, provider access back to comparison and decision support

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Our new user active comparator design and use of rigorous PS matching (including laboratory measurements) method help mitigate indication and confounding bias, and provided information on direct comparisons between therapies, which was a limitation of prior placebo controlled RCTs

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