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It is acknowledged that the stimulation of signal transducers and activators of transcription 3 (STAT3) is essential for the transformation into the M2 subtype, whereas the activation of STAT1 is a crucial determinant for the M1 subtype [85]

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It plays a vital role in transporting fatty acids into the mitochondria, where they are converted into energy

The application of more conservative methods (e.g., Bonferroni correction) in future research would strengthen the conclusions drawn from such findings