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They work similarly and have similar side effects, but the primary difference lies in their intended use and FDA approval

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In one study, 12-week treatment with insulin glargine vs liraglutide (mean dose = 1.3 mg/day) showed similar glycemic control and decrease of hepatic fat burden, although a reduction in BMI was only observed in the liraglutide-treated patients (68)

Oral bioavailability for systemic purposes is estimated at 1030% of injectable delivery

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Understanding GLP-1 Medications What are GLP-1 Receptor Agonists